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Researchers identify new protein linked to leukaemia growth
Their work has identified a protein called PIP4K2A that could be a new target in drug development.Uncontrolled growth of cells is one of the hallmarks of cancer.
In acute myeloid leukaemia, abnormal white blood cells accumulate in the bone marrow, blocking production of normal red and white blood cells.

All blood cells are derived from so-called haematopoietic stem cells, but there are certain molecules – phosphoinositides – that appear to control potential conversion of these stem cells into cancerous leukaemic cells. Some of these phosphoinositides switch on specific cell signalling pathways, resulting in rapid growth and enhanced survival.
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